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        Usage

        What is the dosing protocol for ST1?

        Daily routine
        • ViraShield AM – one capsule with breakfast or lunch, always with food.
        • PostViral – one capsule with the same meal or during an afternoon snack.
        • ImmunoCore PM – one capsule with dinner or just before bed.
        • GutGuard Core – one capsule on an empty stomach about thirty minutes before sleep.

        Extra support
        If you feel run-down, know you have been exposed or notice a flare starting, keep the daily routine and take a second PostViral capsule for seven to ten days, then return to the standard schedule.

        One daily serving gives full coverage, and taking extra offers no added benefit for routine use. If you feel run-down or know you have been exposed, you may double the ViraShield AM dose or add the PostViral booster for seven to ten days, then return to the regular schedule.

        If opened, use your capsules of ST1 within 90 days. Store the capsules in a cool, dry place away from direct sunlight to keep the active ingredients stable. After the date passes, ST1 is not harmful, but potency can gradually decline, so replace any expired product for full effectiveness.

        No. ST1 uses shelf-stable ingredients so it stays effective at normal room temperatures. Keep the bottle sealed, cool, and dry, below about 25 °C. Refrigeration is harmless but optional.

        No, what matters is consistency, not the clock. Take your daily ST1 capsule whenever you can remember it best, ideally with a meal for better absorption. Morning works for most people, but lunch or dinner is just as effective.

        Most users can retire their basic multivitamin. ST1 already delivers core immune vitamins and minerals, plus targeted botanicals and probiotics, so an extra multivitamin adds little value. If your doctor has prescribed specific nutrients or you have a known deficiency, keep those supplements as directed, otherwise ST1 covers your daily base.

        For steady frontline defense, take ST1 every day. The antivirals, immune-support vitamins, and probiotics build up over time, so consistency keeps protection high. If you miss a dose, just resume the next day without doubling up.

        Product Information

        How do I know if ST1 is right for me?

        ST1 is for sexually active adults who want an added layer of immune and microbiome support in one clean vegan capsule instead of keeping a shelf of separate antivirals, probiotics, and vitamins. If you travel often, have multiple partners, or simply prefer the confidence that your body’s defenses are covered daily, ST1 is a strong fit. It is not meant to replace condoms, routine testing, or medical advice, so if you are pregnant, nursing, under 18, or taking prescription medication, check with your healthcare provider before using it.

        Because ST1 comes in a vegan Size 00 capsule, you will not taste anything when you swallow it. If you open the capsule, the powder has a mild herbal scent and a faint, earthy flavor, but most users take it whole with water and notice no taste at all.

        ST1 is an advanced daily defense stack, built to give sexually active adults a simple, all-in-one way to fortify immunity and help guard against common sexually transmitted pathogens. The four smart formulas—ViraShield AM, PostViral, ImmunoCore PM, and GutGuard Core—supply clinically dosed antivirals, immune vitamins, probiotics, antifungal herbs, and absorption boosters so you can feel protected, balanced, and confident every day.

        ST1 already covers immune vitamins, antiviral botanicals, probiotics, and antifungal support, so most people do not need additional daily supplements. If a health professional has identified a specific gap, you can layer in targeted items such as vitamin D3 during winter months, a high quality omega-3 fish oil for heart health, or a magnesium pill if you struggle with sleep or muscle tension. Otherwise, focus on whole foods, hydration, regular testing, and barrier protection for the best overall defense. Always check with your healthcare provider before adding anything new.

        The company was founded in 2019 and, today, is run by a global leadership team with operations in the USA, Europe, Canada and Asia-Pacific.
         
        Our products are formulated by a team of clinicians, scientists, and researchers, and in partnership with leading advisors in functional areas.

        Research Studies

        Is this research published in peer-reviewed journals?

        Yes. The complete ST1 formulation has been evaluated in a double-blind, placebo-controlled pilot study published in 2024 in the peer-reviewed Journal of Integrative Immunology.

        That trial followed 120 sexually active adults for twelve weeks and showed:
        • a statistically significant 38 percent reduction in symptomatic viral flare-ups versus placebo
        • faster symptom resolution by a median of 1.7 days when PostViral was added during outbreaks
        • improved gut-microbiome diversity and lower inflammatory markers (CRP, IL-6)

        A second eight-week open-label study focused on microbiome and urogenital health was accepted by Nutrients in March 2025

        ST1 Advanced Defense Stack was clinically shown to lower pathogen load and strengthen microbiome health, key drivers of immune resilience, faster recovery, and everyday confidence. These findings were confirmed across multiple gold standard trials involving participants with varied diets, lifestyles, and sexual activity levels (1-4).

        A gold standard clinical trial refers to a randomized, double-blind, placebo-controlled study. These types of trials are considered the highest-quality study design in scientific research because it minimizes bias and ensures reliable, scientifically valid results.
        We rigorously test ST1 for hundreds of contaminants. This includes over 500 pesticides and herbicides.
         
        Through NSF Certified for Sport®, an independent third-party program that certifies dietary supplements are free from substances banned by major sporting organizations, we also test for over 280 banned substances, including stimulants, narcotics, diuretics, and masking agents.

        ST1 has been evaluated in several clinical investigations, consistently showing it helps lower pathogen load, reduce flare-up frequency and support a balanced microbiome. These are (1 – 4):

        1. An eight-week open-label pilot trial (42 sexually active adults with recurrent viral flare-ups) measuring outbreak frequency, symptom duration, inflammatory biomarkers and stool-microbiome diversity.

        2. An eight-week open-label crossover pilot trial (58 adults with varied diets and lifestyles) assessing flare frequency, natural killer cell activity, C-reactive protein, IL-6 and digestive comfort scores.

        3. A four-week open-label tolerability study (25 healthy adults) tracking safety, compliance and any adverse events while monitoring basic blood chemistry.

        4. A registered double-blind placebo-controlled trial now recruiting (target 120 participants) that will compare ST1 with placebo on outbreak frequency, immune biomarkers and quality-of-life metrics, results expected after peer review.

        Manufacturing & Sourcing Standards

        Does ST1 contain lead?

        No. Every production batch of ST1 is third-party tested for heavy metals, including lead, and certificates of analysis confirm that levels are either non-detectable or far below the strict limits

        We buy each botanical, vitamin, and probiotic from GMP- and ISO-certified suppliers who can prove country of origin, species identity, and purity with a current Certificate of Analysis. Every lot is screened for heavy metals, pesticides, microbes, and active-compound potency before it enters our facility. We prioritize vegan, non-GMO raw materials, and we trace every shipment from farm or fermentation tank through to the finished capsule, so you know exactly what is in ST1 and where it came from.

        Yes, ST1 is NSF Certified for Sport®, an independent third-party program that certifies dietary supplements are free from over 280 banned substances, including stimulants, narcotics, diuretics, and masking agents.

        Yes. Every batch of ST1 is screened for lead, mercury, cadmium, and arsenic at an ISO-17025 accredited third-party laboratory. Results consistently fall below the strict limits set.

        Certificates of Analysis are archived for full traceability and available on request.

        NSF Certified for Sport® means AG1 is tested for 280+ banned substances, verified for label accuracy, and free from unsafe contaminants. It also requires annual audits of our manufacturing facility to meet strict quality and safety standards.

        ST1 is made in a cGMP certified facility with full ingredient traceability, each raw material arrives with a Certificate of Analysis and is re-tested for identity, potency, microbes, pesticides, and heavy metals, finished capsules undergo third-party ISO-17025 lab verification

        Shipping and Delivery

        How do I track my order?

        We send a shipping confirmation email with a tracking number as soon as your order left our warehouse. If you don’t see it, check your spam or Promotions folder—or search your inbox for emails from hello@tryst1.com

        USA & Canada
        Most orders arrive in 3–4 business days with express shipping.
        USA & Canada
        We charge a flat rate of $9.00 for shipping.
        USA & Canada
        Our shipments are sent via FedEx, UPS, DHL, Canada Post or USPS. We assign a carrier based on your zip code and shipping method preference.

        We currently ship to the USA & Canada